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acetylcholine modulation of hippocampal memory function

Candidate: concept label1 source documents4 linked claims
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Extracted Explainers

What the tool is doing

This concept captures the review's focus on how acetylcholine influences hippocampal circuits and memory-related function.

Source 1DOIPubMed

What problem it solves

It provides a high-level organizing label for literature on cholinergic regulation of hippocampus-dependent learning.

Source 1DOIPubMed

What it does not solve

It does not itself specify a discrete experimental tool, construct, or assay.

Source 1DOIPubMed

Alternatives

Nearby concepts in the supplied summary include septohippocampal acetylcholine, receptor-specific muscarinic and nicotinic signaling, and network-state regulation such as theta and sharp-wave ripples.

Source 1DOIPubMed

Evidence Snippets

Acetylcholine (ACh) plays an important role in memory function... Cholinergic neurons densely innervate the hippocampus, mediating the formation of episodic as well as semantic memory. Here, we will review recent findings on acetylcholine's modulation of memory function, with a particular focus on hippocampus-dependent learning, and the circuits involved.
Evidence 1Source 1DOIPubMedprovenance

Supporting Sources

Linked Claims

Claim 1review summarysupports2017Source 1DOIPubMed

Acetylcholine actions in memory function are complex.

Claim 2review summarysupports2017Source 1DOIPubMed

Acetylcholine plays an important role in memory function.

Claim 3review summarysupports2017Source 1DOIPubMed

Cholinergic neurons densely innervate the hippocampus and mediate the formation of episodic and semantic memory.

Claim 4review summarysupports2017Source 1DOIPubMed

Impairment of hippocampus-dependent learning strongly manifests in aging-related dementia, in which acetylcholine has been implicated.