Alkaloids are named as one of the natural chemical classes associated with HIF-1α inhibition in the review. The abstract treats them as a broad category.
First-pass extracted concept
alkaloids
Candidate: concept label2 source documents3 linked claims
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Metabolites, such as sulfated polysaccharides, lectins, alkaloids, and terpenoids, display inhibitory activity across multiple stages of the HIV life cycle
Increasing evidence suggests that natural chemicals, such as polyphenols, isothiocyanates, curcumin, and alkaloids, are inhibitors of HIF-1α.
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Marine-derived compounds investigated as anti-HIV agents show inhibitory activity across multiple stages of the HIV life cycle, including viral entry, reverse transcription, integration, and maturation.
Quoted textsource-backed
Metabolites, such as sulfated polysaccharides, lectins, alkaloids, and terpenoids, display inhibitory activity across multiple stages of the HIV life cycle, including viral entry, reverse transcription, integration, and maturation.
Recent discoveries validate marine ecosystems as useful hit and compound sources for anti-HIV drug discovery.
Quoted textsource-backed
recent discoveries showcase the chemical diversity of marine ecosystems and validate their utility as hit and compound sources in drug discovery
Natural chemicals including polyphenols, isothiocyanates, curcumin, and alkaloids are described as inhibitors of HIF-1α.