First-pass extracted concept

amygdala-liver axis

Candidate: concept label1 source documents3 linked claims

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Evidence Snippets

Our findings reveal an amygdala-liver axis that regulates rapid glycaemic adaptations to stress and links recurrent stress to metabolic dysfunction.

Evidence 1Source 1DOI PubMedprovenance

Supporting Sources

Source 1primary paper2025MEDDOI PubMed

1 evidence snippet 3 linked claims Claim 1 Claim 2 Claim 3

Linked Claims

Claim 1connectivity mappingsupports2025Source 1DOI PubMed

Whole-body virus tracing identified a polysynaptic connection from the medial amygdala to the liver that promotes rapid glucose synthesis by hepatic gluconeogenesis.

Claim 2disease linksupports2025Source 1DOI PubMed

Repeated stress exposure disrupts medial amygdala control of blood glucose, resulting in diabetes-like dysregulation of glucose homeostasis.

Claim 3physiological rolesupports2025Source 1DOI PubMed

An amygdala-liver axis regulates rapid glycaemic adaptations to stress and links recurrent stress to metabolic dysfunction.