First-pass extracted concept

anterior cingulate cortex-centrolateral thalamus accessory neurocircuit

Candidate: concept label1 source documents3 linked claims

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Aliases

ACC-CL neurocircuit, accessory prefrontal cortex-thalamus circuit

Evidence Snippets

These results reveal an ACC-CL neurocircuit as an accessory loop in virgin females for the initiation of maternal care upon first-time exposure to pups.

Evidence 1Source 1DOI PubMedprovenance

Supporting Sources

Source 1primary paper2022MEDDOI PubMed

1 evidence snippet 3 linked claims Claim 1 Claim 2 Claim 3

Linked Claims

Claim 1circuit modelsupports2022Source 1DOI PubMed

An ACC-CL neurocircuit functions as an accessory loop for initiation of maternal care in virgin females upon first-time pup exposure.

Quoted textsource-backed

These results reveal an ACC-CL neurocircuit as an accessory loop in virgin females for the initiation of maternal care upon first-time exposure to pups.

Claim 2mechanistic dependencysupports2022Source 1DOI PubMed

Anterior cingulate cortex activity depends on feedback excitation from centrolateral thalamus Vglut2+/Galanin+ neurons.

Quoted textsource-backed

ACC activity is dependent on feedback excitation by Vglut2+ /Galanin+ neurons of the centrolateral nucleus of the thalamus (CL)

Claim 3mechanistic rolesupports2022Source 1DOI PubMed

In virgin female mice, development of maternal care behavior upon first-time pup exposure is initiated by activation of the anterior cingulate cortex.

Quoted textsource-backed

Here, we show that the development of maternal care behavior in response to first-time pup exposure in virgin females is initiated by the activation of the anterior cingulate cortex (ACC).