First-pass extracted concept

anti-resonance

Candidate: concept label1 source documents4 linked claims

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Evidence Snippets

We find that cells exhibit a minimal response to Wnt at certain frequencies, a behavior we term anti-resonance.

Evidence 1Source 1DOI PubMedprovenance

Supporting Sources

Source 1primary paper2026MEDDOI PubMed

1 evidence snippet 4 linked claims Claim 1 Claim 2 Claim 3

Linked Claims

Claim 1biological interpretationsupports2026Source 1DOI PubMed

Anti-resonance may act as a filter against spurious Wnt pathway activation.

Claim 2cell fate effectsupports2026Source 1DOI PubMed

Signal frequency directly influences human gastrulation-related cell fate decisions, and anti-resonant frequencies dramatically reduce mesoderm differentiation.

Claim 3mechanistic observationsupports2026Source 1DOI PubMed

Cells show a minimal Wnt response at certain stimulation frequencies, termed anti-resonance.

Claim 4model based mechanismsupports2026Source 1DOI PubMed

Detailed biochemical and simplified hidden variable models explain anti-resonance as emerging from interplay between fast and slow pathway dynamics.