First-pass extracted concept

Arc

Candidate: concept label2 source documents3 linked claims

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Aliases

arc

Evidence Snippets

The supplied web research summary states that Arc appears in the anchor review as a plasticity-linked molecule with possible broader memory roles.

Evidence 1Source 1DOI PubMedprovenance

Immediate Early Genes (IEGs) such as, c-fos, Egr1 and arc are selectively and promptly upregulated in learning and memory among neuronal subpopulations in regions associated with these processes.

Evidence 2Source 2DOI PubMedprovenance

Supporting Sources

Source 1review2019npj Science of LearningDOI PubMed

1 evidence snippet 0 linked claims

Source 2review2018Frontiers in Behavioral NeuroscienceDOI PubMed

1 evidence snippet 3 linked claims Claim 1 Claim 2 Claim 3

Linked Claims

Claim 1evidence gapsupports2018Source 2DOI PubMed

Although many studies support changes in immediate early gene expression during learning and memory, few studies directly analyze the implication of these genes in mental illnesses.

Claim 2expression associationsupports2018Source 2DOI PubMed

Immediate early genes including c-Fos, Egr1, and Arc are selectively and rapidly upregulated during learning and memory in neuronal subpopulations associated with these processes.

Claim 3memory process associationsupports2018Source 2DOI PubMed

Changes in expression of c-Fos, Egr1, and Arc have been observed in recognition, working, and fear-related memories across the brain.