First-pass extracted concept

Arylative bioconjugation

Candidate: concept label1 source documents3 linked claims

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Evidence Snippets

Here we outline and review sulfur, nitrogen, selenium, oxygen, and carbon arylative bioconjugation strategies and their applications to modify peptides, proteins, sugars, and nucleic acids.

Evidence 1Source 1DOI PubMedprovenance

Supporting Sources

Source 1review2018Angewandte Chemie International EditionDOI PubMed

1 evidence snippet 3 linked claims Claim 1 Claim 2 Claim 3

Linked Claims

Claim 1design principlesupports2018Source 1DOI PubMed

Effective bioconjugation reactions require high efficiency and selectivity under mild, biomolecule-compatible conditions.

Claim 2functional promisesupports2018Source 1DOI PubMed

Methods that form nucleophile-sp2 carbon bonds show promise for creating bioconjugates with new modifications and sometimes unparalleled functions.

Claim 3review scopesupports2018Source 1DOI PubMed

The review surveys sulfur, nitrogen, selenium, oxygen, and carbon arylative bioconjugation strategies and their applications to peptides, proteins, sugars, and nucleic acids.