These studies suggest that astrocytes represent a diverse population of cells and that they display brain area- and disease-specific properties and functions.
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astrocyte diversity
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Recent availability of RNA sequencing, immunohistochemistry, electron microscopy, morphological reconstruction, and imaging data has challenged the view that astrocytes are a homogeneous population across the CNS.
The reviewed studies suggest that astrocytes are a diverse population with brain area-specific and disease-specific properties and functions.
Knowledge gaps remain before astrocyte diversity can be fully exploited as a physiologically relevant biological phenomenon in the CNS.