First-pass extracted concept

autoimmune encephalitides

Candidate: concept label1 source documents4 linked claims
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Aliases

AEs

Extracted Explainers

What the tool is doing

Autoimmune encephalitides are presented as a recently described group of disorders with neuropsychiatric symptoms, diverse antibodies, and weaker cancer association than PNSs.

Source 1DOIPubMed

What problem it solves

The concept frames the review's discussion of infection-triggered and host-genetic autoimmune mechanisms.

Source 1DOIPubMed

What it does not solve

The abstract does not provide subtype-specific diagnostic workflows or therapeutic algorithms.

Source 1DOIPubMed

Alternatives

The review contrasts AEs with paraneoplastic neurological syndromes.

Source 1DOIPubMed

Evidence Snippets

autoimmune encephalitides (AEs) comprise a recently described group of disorders characterized by prominent neuropsychiatric symptoms, diverse antibody spectrum, and less tight association with cancer
Evidence 1Source 1DOIPubMedprovenance

Supporting Sources

Linked Claims

Claim 1disease comparisonsupports2020Source 1DOIPubMed

Autoimmune encephalitides have a less tight association with cancer than paraneoplastic neurological syndromes.

Quoted textsource-backed
autoimmune encephalitides (AEs) comprise a recently described group of disorders characterized by prominent neuropsychiatric symptoms, diverse antibody spectrum, and less tight association with cancer
Claim 2genetic association summarysupports2020Source 1DOIPubMed

Some autoimmune encephalitides, including LGI1-antibody encephalitis, are associated with specific host-related factors such as HLA.

Quoted textsource-backed
in some AEs (e.g. LGI1-antibody encephalitis) an association with specific host-related factors [e.g., human leukocyte antigen (HLA)] was clearly demonstrated
Claim 3host susceptibility summarysupports2020Source 1DOIPubMed

Selective deficiency in the innate immune system is presented as a susceptibility context for infection-induced neurological autoimmunity.

Quoted textsource-backed
in susceptible individuals (those with a selective deficiency in the innate immune system)
Claim 4triggering factorsupports2020Source 1DOIPubMed

Preceding infections, particularly herpes simplex virus encephalitis, are important in inducing neurological autoimmune disorders in susceptible individuals.

Quoted textsource-backed
Recent data have shed light on the importance of preceding infections (in particular, herpes simplex virus encephalitis) in inducing neurological autoimmune disorders in susceptible individuals