Bacteriophages in gut metagenomes: from analysis to application.
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bacteriophages in gut metagenomes
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Bacteriophages are a major component of the human gut virome and play important roles in shaping the structure and function of the gut microbiota.
Quoted textsource-backed
Bacteriophages constitute a major component of the human gut virome, playing very important roles in shaping of the structure and function of the gut microbiota.
Recent metagenomic sequencing and computational analysis advances have substantially expanded understanding of gut phage diversity and the scale of viral dark matter.
Quoted textsource-backed
Recent advancements in metagenomic sequencing and computational analysis have substantially expanded our understanding of gut phage diversity and the scale of the so-called 'viral dark matter'.
Bacteriophages interact with the human immune system and thereby influence disease processes.
Quoted textsource-backed
Moreover, bacteriophages interact with the human immune system, thereby influencing various disease processes.
Taxonomic classification and host prediction of phages remain key challenges in gut phage metagenomic analysis.
Quoted textsource-backed
discuss key challenges in taxonomic classification and host prediction of phages
Bacteriophages have therapeutic potential in cancer immunotherapy, inflammatory diseases, and liver diseases, and may serve as diagnostic and prognostic biomarkers.
Quoted textsource-backed
We also analyze the therapeutic potential of bacteriophages, including their application in cancer immunotherapy, inflammatory diseases, and liver diseases, and their promise as diagnostic and prognostic biomarkers.