the basal forebrain (BF) cholinergic projections, once viewed as a diffuse system, are emerging as being remarkably specific in connectivity
First-pass extracted concept
basal forebrain–cortical cholinergic circuits
Candidate: concept label1 source documents3 linked claims
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Aliases
BF cholinergic projections, BF cholinergic system
Evidence Snippets
Supporting Sources
Linked Claims
Basal forebrain cholinergic projections are increasingly understood as specifically connected circuits rather than a diffuse projection system.
Quoted textsource-backed
the basal forebrain (BF) cholinergic projections, once viewed as a diffuse system, are emerging as being remarkably specific in connectivity
The basal forebrain cholinergic system has disease-modifying relevance, including established degeneration in Alzheimer's disease and involvement in anxiety-related circuits.
Quoted textsource-backed
the demise of BF cholinergic neurons has long been established in Alzheimer's disease and recent studies have revealed the involvement of the cholinergic system in modulation of anxiety-related circuits
Basal forebrain cholinergic neurons, together with other basal forebrain neurons, provide temporal structure for behavior, regulate local cortical state, and coordinate activity between functionally related cortical circuits.
Quoted textsource-backed
cholinergic neurons, together with other BF neurons, provide temporal structure for behavior, contribute to local cortical state regulation, and coordinate activity between different functionally related cortical circuits