We report the isolation of bcl-x, a bcl-2-related gene that can function as a bcl-2-independent regulator of programmed cell death (apoptosis).
First-pass extracted concept
bcl-x
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Linked Claims
bcl-x is a bcl-2-related gene that can function as a bcl-2-independent regulator of programmed cell death.
Quoted textsource-backed
We report the isolation of bcl-x, a bcl-2-related gene that can function as a bcl-2-independent regulator of programmed cell death (apoptosis).
Alternative splicing of bcl-x produces two distinct mRNAs.
Quoted textsource-backed
Alternative splicing results in two distinct bcl-x mRNAs.
bcl-x has roles in both positive and negative regulation of programmed cell death.
Quoted textsource-backed
Together these data suggest that bcl-x plays an important role in both positive and negative regulation of programmed cell death.