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First-pass extracted concept

Bcl-xL

Candidate: concept label1 source documents4 linked claims
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Aliases

bcl-xL

Evidence Snippets

The protein product of the larger mRNA, bcl-xL, is similar in size and predicted structure to Bcl-2.
Evidence 1Source 1DOIPubMedprovenance

Supporting Sources

Linked Claims

Claim 1expression patternsupports1993Source 1DOIPubMed

bcl-xL is found in tissues containing long-lived postmitotic cells such as adult brain.

Quoted textsource-backed
In contrast, bcl-xL is found in tissues containing long-lived postmitotic cells, such as adult brain.
Claim 2functional effectsupports1993Source 1DOIPubMed

In an IL-3-dependent cell line, stable transfection of bcl-xL inhibits cell death after growth factor withdrawal at least as well as bcl-2.

Quoted textsource-backed
When stably transfected into an IL-3-dependent cell line, bcl-xL inhibits cell death upon growth factor withdrawal at least as well as bcl-2.
Claim 3overall conclusionsupports1993Source 1DOIPubMed

bcl-x has roles in both positive and negative regulation of programmed cell death.

Quoted textsource-backed
Together these data suggest that bcl-x plays an important role in both positive and negative regulation of programmed cell death.
Claim 4structural similaritysupports1993Source 1DOIPubMed

Bcl-xL is similar in size and predicted structure to Bcl-2.

Quoted textsource-backed
The protein product of the larger mRNA, bcl-xL, is similar in size and predicted structure to Bcl-2.