First-pass extracted concept

Bcl-xS

Candidate: concept label1 source documents3 linked claims

Jump to evidence Jump to sources Jump to claims

Live refresh every 5sNext refresh in 5s

Aliases

bcl-xS

Evidence Snippets

Surprisingly, the second mRNA species, bcl-xS, encodes a protein that inhibits the ability of bcl-2 to enhance the survival of growth factor-deprived cells.

Evidence 1Source 1DOI PubMedprovenance

Supporting Sources

Source 1primary paper1993CellDOI PubMed

1 evidence snippet 3 linked claims Claim 1 Claim 2 Claim 3

Linked Claims

Claim 1expression patternsupports1993Source 1DOI PubMed

bcl-xS mRNA is expressed at high levels in cells with high turnover such as developing lymphocytes.

Quoted textsource-backed

In vivo, bcl-xS mRNA is expressed at high levels in cells that undergo a high rate of turnover, such as developing lymphocytes.

Claim 2functional effectsupports1993Source 1DOI PubMed

Bcl-xS inhibits the ability of bcl-2 to enhance survival of growth factor-deprived cells.

Quoted textsource-backed

Surprisingly, the second mRNA species, bcl-xS, encodes a protein that inhibits the ability of bcl-2 to enhance the survival of growth factor-deprived cells.

Claim 3overall conclusionsupports1993Source 1DOI PubMed

bcl-x has roles in both positive and negative regulation of programmed cell death.

Quoted textsource-backed

Together these data suggest that bcl-x plays an important role in both positive and negative regulation of programmed cell death.