First-pass extracted concept

BDNF signaling

Candidate: concept label1 source documents3 linked claims

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Evidence Snippets

In this review, we summarize recent advances in the field of BDNF signaling in neurons to induce neuronal growth.

Evidence 1Source 1DOI PubMedprovenance

Supporting Sources

Source 1review2016CytoskeletonDOI PubMed

1 evidence snippet 3 linked claims Claim 1 Claim 2 Claim 3

Linked Claims

Claim 1knowledge gapsupports2016Source 1DOI PubMed

The cellular and molecular mechanisms underlying BDNF-regulated dendritic and axonal growth are not fully understood.

Claim 2mechanistic scopesupports2016Source 1DOI PubMed

Recent advances in the field implicate neuronal transcription, local protein translation, and cytoskeleton and membrane dynamics in BDNF-mediated structural plasticity and neuronal growth.

Claim 3review scope summarysupports2016Source 1DOI PubMed

BDNF and its receptors TrkB and p75 regulate dendritic and axonal growth during nervous system development and maintenance.