Biomimetic nanomedicines emulate biological membrane structures and functions for cerebral ischemic stroke diagnosis and treatment. The review frames them as a therapeutic approach for CIS management.
First-pass extracted concept
biomimetic nanomedicines
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biomimetic membrane nanotechnology, BMNPs
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Biomimetic membrane nanotechnology is presented as an emerging therapeutic approach for cerebral ischemic stroke by emulating biological membrane structures and functions.
Biomimetic membrane nanotechnology, as an emerging therapeutic approach, offers a novel therapeutic strategy by emulating biological membrane structures and functions.
The reviewed biomimetic nanomaterial classes are described as having capacity to enhance blood-brain barrier penetration, improve target specificity, and evade immune clearance in cerebral ischemic stroke management.
We discussed in detail various types of biomimetic nano-materials such as conventional extracellular membranes, bacterial outer membranes, and virus-like particles, and explore their capacity in enhancing BBB penetration, improving target specificity, and evading immune clearance.
Current challenges for biomimetic membrane nanotechnology in cerebral ischemic stroke include biosafety, manufacturing quality control, targeted modification precision, and controlled drug release kinetics.
Current challenges regarding biosafety profiles, manufacturing quality control, targeted modification precision, and controlled drug release kinetics are delineated in this review.
Cerebral ischemic stroke poses diagnosis and treatment challenges primarily because of blood-brain barrier constraints and inherent drug targeting limitations.
Cerebral ischemic stroke (CIS) is a severe cerebrovascular disease that poses numerous challenges in diagnosis and treatment, primarily attributed to blood-brain barrier (BBB) constraints and inherent drug targeting limitations.