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First-pass extracted concept

brite adipocyte

Candidate: concept label1 source documents5 linked claims
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Aliases

beige adipocyte

Extracted Explainers

What the tool is doing

The brite adipocyte is presented as a proposed adipocyte type with capacity for transdifferentiation. In this review it functions as a lineage and plasticity concept rather than a tool.

Source 1DOI

What problem it solves

It helps explain adipose-organ plasticity beyond a simple brown-versus-white adipocyte dichotomy.

Source 1DOI

What it does not solve

The abstract does not establish a specific assay, construct, or intervention based on brite adipocytes.

Source 1DOI

Alternatives

The abstract contrasts brite adipocytes with brown and white adipocytes.

Source 1DOI

Evidence Snippets

another cell type is suggested to exist, 'brite' adipocyte, holding the capacity of transdifferentiation.
Evidence 1Source 1DOIprovenance

Supporting Sources

Linked Claims

Claim 1cell plasticitysupports2010Source 1DOI

Brown and white adipocytes can transdifferentiate into each other under specific exposure, and a brite adipocyte cell type is suggested to exist with transdifferentiation capacity.

Quoted textsource-backed
brown and white adipocytes transdifferentiate into each other's under specific exposure but in addition, another cell type is suggested to exist, 'brite' adipocyte, holding the capacity of transdifferentiation.
Claim 2functional activitysupports2010Source 1DOI

Adult human brown adipose tissue is functionally active.

Quoted textsource-backed
Human brown adipose tissue (BAT) has recently found to be functionally active in adults.
Claim 3lineage relationshipsupports2010Source 1DOI

Brown adipocytes and myocytes share the same origin.

Quoted textsource-backed
Brown adipocytes and myocytes share the same origin.
Claim 4physiology similaritysupports2010Source 1DOI

Preliminary results suggest that BAT resembles skeletal muscle by origin and by the effect of insulin on the tissue.

Quoted textsource-backed
Preliminary results suggest that BAT resembles skeletal muscle not only by origin but also by the effect of insulin on the tissue.
Claim 5regulatory activationsupports2010Source 1DOI

Factors that increase sympathetic nervous system activity and uncoupling protein 1 may increase BAT activity.

Quoted textsource-backed
Other factors that may increase the activity of sympathetic nervous system and uncoupling protein 1 are several including the complex network of hormonal and neuronal signals.