First-pass extracted concept

calretinin-expressing striatal GABAergic interneurons

Candidate: concept label1 source documents3 linked claims
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Aliases

CR interneurons

Evidence Snippets

The last GABAergic interneuron subtype expresses the calcium binding protein, calretinin. Thus far, no recordings from identified CR interneurons have been obtained.
Evidence 1Source 1DOIPubMedprovenance

Supporting Sources

Linked Claims

Claim 1cell type classificationsupports2010Source 1DOIPubMed

Three distinct striatal GABAergic interneuron subtypes are generally recognized: parvalbumin-expressing, NPY/SOM/NOS-expressing, and calretinin-expressing interneurons.

Quoted textsource-backed
From the anatomical studies, three distinct GABAergic interneuronal subtypes are generally recognized. The best-studied subtype expresses the calcium-binding protein, parvalbumin. The second best known interneuron type expresses a number of neuropeptides and enzymes, including neuropeptide Y, somatostatin, and nitric oxide synthase. The last GABAergic interneuron subtype expresses the calcium binding protein, calretinin.
Claim 2evidence gapsupports2010Source 1DOIPubMed

No recordings from identified calretinin-expressing striatal interneurons had been obtained at the time of this article.

Quoted textsource-backed
Thus far, no recordings from identified CR interneurons have been obtained.
Claim 3marker separationsupports2010Source 1DOIPubMed

The marker sets defining the three classic striatal GABAergic interneuron classes do not overlap or co-localize.

Quoted textsource-backed
There is no overlap or co-localization of these three different sets of markers.