Molecular genetics along with optogenetic and pharmacogenetic tools for perturbing neuron function have enabled cell type-selective dissection of circuits that mediate behavioral responses to physiological state changes.
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cell type-selective circuit dissection
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Molecular genetics together with optogenetic and pharmacogenetic perturbation tools has enabled cell type-selective dissection of neural circuits mediating behavioral responses to physiological state changes.
The neural circuits underlying the crosstalk between physiological state and motivational processes are poorly understood.
The review focuses on a starvation-sensitive hypothalamic neuron population in the mouse that is sufficient to promote voracious eating.