First-pass extracted concept

central extended amygdala

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Evidence Snippets

the central nucleus of the amygdala (Ce) and the bed nucleus of the stria terminalis (BST), the two major subdivisions of the central extended amygdala

Evidence 1Source 1DOI PubMedprovenance

Supporting Sources

Source 1primary paper2016Journal of NeuroscienceDOI PubMed

1 evidence snippet 3 linked claims Claim 1 Claim 2 Claim 3

Linked Claims

Claim 1anatomical relationshipsupports2016Source 1DOI PubMed

Anatomical studies indicate that the Ce and BST form a tightly interconnected unit that can integrate threat-relevant information to assemble states of fear and anxiety.

Quoted textsource-backed

Anatomical studies show that the Ce and BST form a tightly interconnected unit, where different kinds of threat-relevant information can be integrated and used to assemble states of fear and anxiety.

Claim 2conceptual reassessmentsupports2016Source 1DOI PubMed

The paper argues against a strictly dissociable Ce-versus-BST model of phasic fear and sustained anxiety and instead supports viewing them as an integrated central extended amygdala unit.

Quoted textsource-backed

It is widely thought that phasic and sustained responses to threat reflect dissociable circuits centered on the central nucleus of the amygdala (Ce) and the bed nucleus of the stria terminalis (BST)... However, new observations encourage a different perspective. Anatomical studies show that the Ce and BST form a tightly interconnected unit

Claim 3disease relevancesupports2016Source 1DOI PubMed

The reported observations imply that the central extended amygdala has an important role in neuropsychiatric disease.

Quoted textsource-backed

These observations compel a reconsideration of the central extended amygdala's contributions to fear and anxiety and its role in neuropsychiatric disease.