First-pass extracted concept

cephalopod immune system

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Evidence Snippets

This review summarizes the current status of our knowledge about the cephalopod immune system... the advances gained to date point out a complex innate immunity in cephalopods.

Evidence 1Source 1DOI PubMedprovenance

Supporting Sources

Source 1primary paper2015Fish & Shellfish ImmunologyDOI PubMed

1 evidence snippet 5 linked claims Claim 1 Claim 2 Claim 3

Linked Claims

Claim 1environmental impactsupports2015Source 1DOI PubMed

Assessment of immune parameters in cephalopods exposed to contaminants is only beginning, but some pollutants have been reported to negatively affect immune response in the common octopus.

Claim 2knowledge gapsupports2015Source 1DOI PubMed

For many cephalopod immune-related genes and proteins, characterization and precise roles in immune response remain unresolved.

Claim 3localizationsupports2015Source 1DOI PubMed

Many identified cephalopod immune-related genes and proteins have been found in haemocytes and also in gills and digestive gland.

Claim 4molecular discoverysupports2015Source 1DOI PubMed

Improved molecular approaches have enabled discovery of multiple cephalopod immune-related genes and proteins, including antimicrobial peptides, phenoloxidases, antioxidant enzymes, serine protease inhibitor, lipopolysaccharide-induced TNF-alpha factor, Toll-like receptors, lectins, and clusters of differentiation.

Claim 5review summarysupports2015Source 1DOI PubMed

Recent work supports that cephalopods possess a complex innate immune system rather than a simple one.