First-pass extracted concept

CGRP-expressing PBN neurons

Candidate: concept label1 source documents3 linked claims

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Aliases

CGRP(PBN) neurons

Evidence Snippets

Here we identify cholecystokinin (CCK) and noradrenergic, dopamine β-hydroxylase (DBH)-expressing NTS neurons as two separate populations that directly excite CGRP(PBN) neurons.

Evidence 1Source 1DOI PubMedprovenance

Supporting Sources

Source 1primary paper2016Nature CommunicationsDOI PubMed

1 evidence snippet 3 linked claims Claim 1 Claim 2 Claim 3

Linked Claims

Claim 1mechanistic relationshipsupports2016Source 1DOI PubMed

CCK-expressing NTS neurons directly excite CGRP-expressing PBN neurons.

Quoted textsource-backed

Here we identify cholecystokinin (CCK) ... NTS neurons as two separate populations that directly excite CGRP(PBN) neurons.

Claim 2mechanistic relationshipsupports2016Source 1DOI PubMed

DBH-expressing NTS neurons directly excite CGRP-expressing PBN neurons.

Quoted textsource-backed

Here we identify ... noradrenergic, dopamine β-hydroxylase (DBH)-expressing NTS neurons as two separate populations that directly excite CGRP(PBN) neurons.

Claim 3mechanistic relationshipsupports2016Source 1DOI PubMed

Optogenetic results indicate that CCK and DBH neurons in the NTS directly engage CGRP-expressing PBN neurons to promote anorexia.

Quoted textsource-backed

Our optogenetic results reveal that CCK and DBH neurons in the NTS directly engage CGRP(PBN) neurons to promote anorexia.