First-pass extracted concept

class III multidendritic neurons

Candidate: concept label1 source documents3 linked claims

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Aliases

CIII md neurons

Evidence Snippets

Recent studies in <i>Drosophila</i> larvae have revealed that somatosensory class III multidendritic (CIII md) neurons function as multimodal sensors regulating distinct behavioral responses to innocuous mechanical and nociceptive thermal stimuli.

Evidence 1Source 1DOI PubMedprovenance

Supporting Sources

Source 1primary paper2025MEDDOI PubMed

1 evidence snippet 3 linked claims Claim 1 Claim 2 Claim 3

Linked Claims

Claim 1activity readoutsupports2025Source 1DOI PubMed

Optogenetic activation of CIII md neurons evokes calcium increases in these neurons.

Claim 2coactivation effectsupports2025Source 1DOI PubMed

Co-activation of CIII md neurons with additional cell types facilitates larval contraction responses.

Claim 3perturbation effectsupports2025Source 1DOI PubMed

Neural silencing of cell types downstream of CIII md neurons significantly reduces cold-evoked behaviors.