First-pass extracted concept

cleavage and polyadenylation complex

Candidate: concept label2 source documents2 linked claims

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Aliases

CPAC

Evidence Snippets

Poly(A) tails of newly synthesized mRNAs have uniform lengths, arising through cooperation between the cleavage and polyadenylation complex (CPAC) and poly(A) binding proteins (PABPs).

Evidence 1Source 1DOIprovenance

Poly(A) tails of newly synthesized mRNAs have uniform lengths, arising through cooperation between the cleavage and polyadenylation complex (CPAC) and poly(A) binding proteins (PABPs).

Evidence 2Source 2DOI PubMedprovenance

Supporting Sources

Source 1primary paper2025PPRDOI

1 evidence snippet 1 linked claim Claim 1

Source 2primary paper2025MEDDOI PubMed

1 evidence snippet 1 linked claim Claim 1

Linked Claims

Claim 1mechanismsupports2025Source 1DOI

Mature poly(A) tail length is determined by kinetic competition between CPAC-mediated tail elongation and Nab2 RNA binding rather than by the Nab2 RNA footprint.

Claim 2mechanismsupports2025Source 2DOI PubMed

Mature poly(A) tail length is determined by kinetic competition between CPAC-mediated tail elongation and Nab2 RNA binding rather than by the Nab2 RNA footprint.