First-pass extracted concept

cognitive behavioral therapy for insomnia

Candidate: concept label1 source documents4 linked claims

Jump to explainers Jump to evidence Jump to sources Jump to claims

Live refresh every 5sNext refresh in 5s

Aliases

CBT-I

Extracted Explainers

What the tool is doing

CBT-I is presented in the supplied review scaffold as a non-pharmacological intervention relevant to chronic pain with comorbid sleep disturbance.

Source 1DOI PubMed

Resources required

Implementation requires access to a structured behavioral insomnia treatment approach; the abstract does not specify delivery format or protocol details.

Source 1DOI PubMed

What problem it solves

It is relevant when chronic pain co-occurs with insomnia or other sleep disturbances.

Source 1DOI PubMed

What it does not solve

The provided source text does not establish that CBT-I directly addresses all pain mechanisms discussed in the review.

Source 1DOI PubMed

Alternatives

The abstract states that both pharmacological and non-pharmacological approaches are reviewed, but does not name specific pharmacological comparators.

Source 1DOI PubMed

Evidence Snippets

Additional high-signal enrichment leads include ... clinical evidence on interventions explicitly discussed in the anchor review, especially CBT-I

Evidence 1Source 1DOI PubMedprovenance

Supporting Sources

Source 1review2019NeuropsychopharmacologyDOI PubMed

1 evidence snippet 4 linked claims Claim 1 Claim 2 Claim 3

Linked Claims

Claim 1clinical scopesupports2019Source 1DOI PubMed

The review covers both pharmacological and non-pharmacological approaches for managing chronic pain comorbid with sleep disturbances and for managing postoperative pain.

Quoted textsource-backed

In addition, it will provide a broad overview of pharmacological and non-pharmacological approaches for the management of chronic pain comorbid with sleep disturbances and for the management of postoperative pain

Claim 2clinical scopesupports2019Source 1DOI PubMed

The review discusses effects of sleep-disturbing medications on pain amplification.

Quoted textsource-backed

as well as discuss the effects of sleep-disturbing medications on pain amplification

Claim 3mechanistic scopesupports2019Source 1DOI PubMed

The review summarizes neurobiological mechanisms by which sleep deficiency may modulate pain, including opioid, monoaminergic, orexinergic, immune, melatonin, endocannabinoid, hypothalamus-pituitary-adrenal axis, adenosine, and nitric oxide signaling pathways.

Quoted textsource-backed

The review that follows will provide an overview of the neurobiological evidence of mechanisms thought to be involved in the modulation of pain by sleep deficiency, including the opioid, monoaminergic, orexinergic, immune, melatonin, and endocannabinoid systems; the hypothalamus-pituitary-adrenal axis; and adenosine and nitric oxide signaling.

Claim 4relationshipsupports2019Source 1DOI PubMed

Pain can be both a cause and a consequence of sleep deficiency.

Quoted textsource-backed

Pain can be both a cause and a consequence of sleep deficiency.