The corticohippocampal circuit is presented as the circuit framework through which information flow between entorhinal cortex and hippocampus is organized. The review uses it to connect anatomy, synaptic plasticity, and memory functions.
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corticohippocampal circuit
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Information flow in the entorhinal cortex-hippocampal loop is organized through circuit design, and corticohippocampal and intrahippocampal microcircuits contribute to learning.
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Here, we discuss how information flow in the EC-hippocampal loop is organized through circuit design. We highlight recently identified corticohippocampal and intrahippocampal connections and how these long-range and local microcircuits contribute to learning.
Learning-related synaptic plasticity within the corticohippocampal circuit during sensory experiences may enable adaptive behaviors for encoding spatial, episodic, social, and contextual memories.
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Finally, we offer insights about how learning-related synaptic plasticity within the corticohippocampal circuit during sensory experiences may enable adaptive behaviors for encoding spatial, episodic, social, and contextual memories.
Patterned activity and coincident inputs give rise to associational plasticity and long-term regulation of information flow in corticohippocampal synaptic transmission.
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A key point to emerge from these studies is that patterned activity and interaction of coincident inputs gives rise to associational plasticity and long-term regulation of information flow.