they offer a promising alternative to protein-based systems such as TetON/OFF or CRISPR-Cas.
First-pass extracted concept
CRISPR-Cas
Candidate: concept label3 source documents5 linked claims
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Evidence Snippets
The field has evolved from protein-based systems (e.g., zinc finger nucleases and transcription activator-like effector nucleases) to RNA-guided systems (e.g., CRISPR-Cas) that can control both genetic and epigenetic states.
PubMed indexes the editorial with the keyword 'crispr cas', and the source PDF notes FungalBraid toolkit support for CRISPR/Cas systems.
Supporting Sources
Linked Claims
Synthetic riboswitches offer a promising alternative to protein-based systems such as TetON/OFF or CRISPR-Cas.
CRISPR-Cas is described here as able to control both genetic and epigenetic states.
Quoted textsource-backed
RNA-guided systems (e.g., CRISPR-Cas) that can control both genetic and epigenetic states.
The field is described as having evolved from protein-based systems such as zinc finger nucleases and TALENs to RNA-guided systems such as CRISPR-Cas.
Quoted textsource-backed
The field has evolved from protein-based systems (e.g., zinc finger nucleases and transcription activator-like effector nucleases) to RNA-guided systems (e.g., CRISPR-Cas)
The source explicitly mentions FungalBraid as a GoldenBraid-compatible modular cloning platform for filamentous fungi with CRISPR/Cas support.
This editorial covers recent advances in applying synthetic biology to production of bioactive compounds.