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First-pass extracted concept

CRISPR/Cas9-based multiplex genome editing

Candidate: concept label1 source documents3 linked claims
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Aliases

MGE

Extracted Explainers

What the tool is doing

CRISPR/Cas9-based multiplex genome editing is described as editing multiple gene loci to pyramid and precisely regulate multiple crop traits. The review frames it as a major enabling approach for modern crop breeding.

Source 1DOIPubMed

Resources required

The abstract supports that the approach relies on CRISPR/Cas-based multiplex editing strategies targeting multiple loci. Specific vectors, delivery systems, or assay requirements are not given in the abstract.

Source 1DOIPubMed

What problem it solves

It addresses the need to improve yield, quality, and stress resistance together rather than optimizing only one trait at a time.

Source 1DOIPubMed

Alternatives

The abstract contrasts multiplex genome editing with traditional crop breeding methods, stating that traditional methods can no longer meet modern agricultural needs.

Source 1DOIPubMed

Evidence Snippets

Over the past decade, CRISPR/Cas9-based multiplex genome editing (MGE) has enabled efficient pyramiding and precise regulation of multiple traits via targeted editing of multiple gene loci, revolutionizing crop breeding.
Evidence 1Source 1DOIPubMedprovenance

Supporting Sources

Linked Claims

Claim 1application scopesupports2026Source 1DOIPubMed

Applications of multiplex genome editing in crop breeding include enhancing stress resistance, increasing yield, and improving quality.

Claim 2capabilitysupports2026Source 1DOIPubMed

CRISPR/Cas9-based multiplex genome editing enables efficient pyramiding and precise regulation of multiple crop traits by targeted editing of multiple gene loci.

Claim 3problem statementsupports2026Source 1DOIPubMed

Improving a single trait is no longer sufficient for modern agricultural production and consumer expectations, making multiple-trait breeding a key objective in current crop breeding.