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CRISPR gene editing

Candidate: concept label2 source documents2 linked claims
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Aliases

clustered regularly interspaced short palindromic repeats gene editing, CRISPR gene editing method

Extracted Explainers

What the tool is doing

CRISPR gene editing is mentioned as part of the future perspective for cellular immunotherapy in plasma cell disorders.

Source 1DOIPubMed

The abstract names CRISPR gene editing as a modality used in autologous HSC gene therapy for sickle cell disease. It is presented alongside lentiviral approaches as part of the therapeutic development landscape.

Source 2DOIPubMed

What problem it solves

The abstract supports only that it contributes to future directions, not a specific solved problem.

Source 1DOIPubMed

Alternatives

Other future-oriented strategies named in the abstract include dual-target treatments, combination therapy, and gamma-secretase inhibitor incorporation.

Source 1DOIPubMed

Evidence Snippets

The CRISPR gene editing method contributes to future perspectives.
Evidence 1Source 1DOIPubMedprovenance
autologous HSC gene therapy was developed using patients' own HSCs with ... clustered regularly interspaced short palindromic repeats gene editing
Evidence 2Source 2DOIPubMedprovenance

Supporting Sources

Linked Claims

Claim 1future directionsupports2026Source 1DOIPubMed

CRISPR gene editing contributes to future perspectives in cellular immunotherapy for plasma cell disorders.

Claim 2modality descriptionsupports2025Source 2DOIPubMed

Autologous HSC gene therapy for sickle cell disease uses patients' own HSCs with lentiviral gene addition or silencing and CRISPR gene editing, making gene therapy applicable to most patients.

Quoted textsource-backed
autologous HSC gene therapy was developed using patients' own HSCs with lentiviral gene addition/silencing and clustered regularly interspaced short palindromic repeats gene editing, making gene therapy applicable to most patients