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Cumulative energy exposure

Candidate: concept label1 source documents3 linked claims
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Extracted Explainers

What the tool is doing

Cumulative energy exposure is the study's exposure framing variable, defined as the product of spatial-peak pulse-average intensity, sonication duration, and duty cycle.

Source 1DOIPubMed

Resources required

Using this concept requires measuring or specifying intensity, sonication duration, and duty cycle.

Source 1DOIPubMed

What problem it solves

It helps organize the reported switch between excitation and suppression under different ultrasound settings.

Source 1DOIPubMed

Evidence Snippets

The cumulative energy exposure is calculated as the product of the spatial-peak pulse-average intensity, SD, and DC.
Evidence 1Source 1DOIPubMedprovenance

Supporting Sources

Linked Claims

Claim 1dose responsesupports2025Source 1DOIPubMed

Higher cumulative energy exposure suppresses gastrocnemius EMG activity during rat sciatic nerve ultrasound neuromodulation.

Quoted textsource-backed
Our findings demonstrate that higher cumulative energy exposure suppresses EMG activity in the gastrocnemius muscle (innervated by the sciatic nerve).
Claim 2dose responsesupports2025Source 1DOIPubMed

Lower cumulative energy exposure enhances motor stimulation during rat sciatic nerve ultrasound neuromodulation.

Quoted textsource-backed
However, lower cumulative energy exposure enhances motor stimulation.
Claim 3state switchsupports2025Source 1DOIPubMed

Ultrasound sonication can switch electrically evoked EMG activity from excitation to suppression depending on acquired cumulative energy.

Quoted textsource-backed
our results show a switch from excitation to suppression of electrically evoked EMG activity following ultrasound sonication depending on the acquired cumulative energy