First-pass extracted concept

D2R-striatopallidal neurons

Candidate: concept label1 source documents4 linked claims
Live refresh every 5sNext refresh in 5s

Aliases

D(2)R-striatopallidal neurons

Evidence Snippets

contribution of D(2)R-striatopallidal and D(1)R-striatonigral neurons in the dorsomedial (DMS, associative) and dorsolateral (DLS, sensorimotor) striatum to distinct functions remains elusive
Evidence 1Source 1DOIPubMedprovenance

Supporting Sources

Linked Claims

Claim 1drug response requirementsupports2011Source 1DOIPubMed

Associative striatum D2R neurons are required for the cataleptic effect of haloperidol and for amphetamine motor response sensitization.

Quoted textsource-backed
Finally, associative striatum D(2)R neurons are required for the cataleptic effect of the typical neuroleptic drug haloperidol and for amphetamine motor response sensitization.
Claim 2functional rolesupports2011Source 1DOIPubMed

Associative striatum exerts population-selective control over locomotion and reactivity to novelty, with striatopallidal neurons inhibiting exploration and striatonigral neurons stimulating exploration.

Quoted textsource-backed
We found that associative striatum exerts a population-selective control over locomotion and reactivity to novelty, striatopallidal and striatonigral neurons inhibiting and stimulating exploration, respectively.
Claim 3functional rolesupports2011Source 1DOIPubMed

DMS-striatopallidal neurons are involved only in early motor learning.

Quoted textsource-backed
Further, DMS-striatopallidal neurons are involved only in early motor learning
Claim 4organizational principlesupports2011Source 1DOIPubMed

The data provide direct experimental evidence for cell-specific topographic functional organization of the dorsal striatum.

Quoted textsource-backed
Altogether, these data provide direct experimental evidence for cell-specific topographic functional organization of the dorsal striatum.