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DBH-expressing NTS neurons

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Aliases

noradrenergic DBH-expressing NTS neurons

Evidence Snippets

Here we identify cholecystokinin (CCK) and noradrenergic, dopamine β-hydroxylase (DBH)-expressing NTS neurons as two separate populations that directly excite CGRP(PBN) neurons.
Evidence 1Source 1DOIPubMedprovenance

Supporting Sources

Linked Claims

Claim 1functional effectsupports2016Source 1DOIPubMed

Activation of CCK-expressing and DBH-expressing NTS neurons using optogenetic or chemogenetic methods decreases food intake.

Quoted textsource-backed
When these NTS neurons are activated using optogenetic or chemogenetic methods, food intake decreases
Claim 2functional effectsupports2016Source 1DOIPubMed

Chronic stimulation of these NTS neuron populations causes mice to lose body weight.

Quoted textsource-backed
with chronic stimulation mice lose body weight
Claim 3mechanistic relationshipsupports2016Source 1DOIPubMed

DBH-expressing NTS neurons directly excite CGRP-expressing PBN neurons.

Quoted textsource-backed
Here we identify ... noradrenergic, dopamine β-hydroxylase (DBH)-expressing NTS neurons as two separate populations that directly excite CGRP(PBN) neurons.
Claim 4mechanistic relationshipsupports2016Source 1DOIPubMed

Optogenetic results indicate that CCK and DBH neurons in the NTS directly engage CGRP-expressing PBN neurons to promote anorexia.

Quoted textsource-backed
Our optogenetic results reveal that CCK and DBH neurons in the NTS directly engage CGRP(PBN) neurons to promote anorexia.