Neocortical pyramidal neurons with somata in layers 5 and 6 are among the most visually striking and enigmatic neurons in the brain. These deep-layer pyramidal neurons (DLPNs) integrate a plethora of cortical and extracortical synaptic inputs along their impressive dendritic arbors.
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deep-layer pyramidal neurons
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DLPNs
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The review organizes deep-layer pyramidal neurons into two broad projection-defined subpopulations: intratelencephalic neurons and extratelencephalic neurons.
Quoted textsource-backed
Here we revisit two broad DLPN subpopulations: those that send their axons within the telencephalon (intratelencephalic neurons) and those that project to additional target areas outside the telencephalon (extratelencephalic neurons).
Increasing ability to selectively target and manipulate deep-layer output neuron subtypes is advancing understanding of their distinct functional contributions.
Quoted textsource-backed
our increasing ability to selectively target and manipulate these output neuron subtypes advances our understanding of their distinct functional contributions
Deep-layer pyramidal neurons in neocortical layers 5 and 6 integrate cortical and extracortical synaptic inputs along extensive dendritic arbors.
Quoted textsource-backed
These deep-layer pyramidal neurons (DLPNs) integrate a plethora of cortical and extracortical synaptic inputs along their impressive dendritic arbors.
The pattern of cortical output to local and long-distance targets is shaped by the unique physiological properties of specific deep-layer pyramidal neuron subpopulations.
Quoted textsource-backed
The pattern of cortical output to both local and long-distance targets is sculpted by the unique physiological properties of specific DLPN subpopulations.