stimulation of cholinergic MSDB neurons in urethane-anesthetized mice acts on hippocampal networks via two distinct pathways
First-pass extracted concept
direct and indirect cholinergic septo-hippocampal pathways
Candidate: concept label1 source documents5 linked claims
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Aliases
direct septo-hippocampal cholinergic projection, indirect pathway, two distinct pathways
Evidence Snippets
Supporting Sources
Linked Claims
Activation of both pathways reduces pyramidal neuron firing and increases precision of coupling to the theta oscillatory phase.
Quoted textsource-backed
Activation of both pathways causes a reduction in pyramidal neuron firing and a more precise coupling to the theta oscillatory phase.
The two anatomically and functionally distinct pathways are likely relevant for cholinergic control of encoding versus retrieval modes in the hippocampus.
Quoted textsource-backed
These two anatomically and functionally distinct pathways are likely relevant for cholinergic control of encoding versus retrieval modes in the hippocampus.
A direct septo-hippocampal cholinergic projection increases firing of hippocampal inhibitory interneurons and decreases firing of principal cells.
Quoted textsource-backed
A direct septo-hippocampal cholinergic projection causes increased firing of hippocampal inhibitory interneurons with concomitantly decreased firing of principal cells.
Cholinergic neurons recruit noncholinergic neurons within the MSDB, and this indirect pathway is required for hippocampal theta synchronization.
Quoted textsource-backed
In addition, cholinergic neurons recruit noncholinergic neurons within the MSDB. This indirect pathway is required for hippocampal theta synchronization.
Stimulation of cholinergic MSDB neurons acts on hippocampal networks via two distinct pathways.
Quoted textsource-backed
In this study, we show that stimulation of cholinergic MSDB neurons in urethane-anesthetized mice acts on hippocampal networks via two distinct pathways.