Here, we review the roles of the monoamines dopamine (DA), norepinephrine (NE), serotonin (5-HT), and other neuromodulators in controlling the activity of the ACC.
First-pass extracted concept
dopamine
Candidate: concept label2 source documents6 linked claims
Live refresh every 5sNext refresh in 5s
Aliases
DA
Evidence Snippets
Dopamine (DA) is a key neurotransmitter involved in multiple physiological functions including motor control, modulation of affective and emotional states, reward mechanisms, reinforcement of behavior, and selected higher cognitive functions.
Supporting Sources
Linked Claims
Chronic pain alters neuromodulator signaling in anterior cingulate cortex circuits to promote pathological hyperexcitability.
Quoted textsource-backed
how chronic pain alters their signaling in ACC circuits to promote pathological hyperexcitability
Dopamine, norepinephrine, serotonin, and other neuromodulators control activity of the anterior cingulate cortex.
Quoted textsource-backed
we review the roles of the monoamines dopamine (DA), norepinephrine (NE), serotonin (5-HT), and other neuromodulators in controlling the activity of the ACC
The review states that dysfunction in dopaminergic transmission is a core alteration in Parkinson's disease, schizophrenia, bipolar disorder, ADHD, and addiction.
Dopamine is described as a key neurotransmitter involved in motor control, affective and emotional state modulation, reward mechanisms, behavioral reinforcement, and selected higher cognitive functions.
The review frames dopamine as a neuromodulator of long-term potentiation and long-term depression in several cortical and subcortical areas.
The review states that dopamine's effects on dendritic spines place it at the interface between motor and cognitive systems.