First-pass extracted concept

dorsal paired medial (DPM) neurons

Candidate: concept label1 source documents4 linked claims

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Aliases

DPM neurons

Evidence Snippets

Here, we show the dorsal paired medial (DPM) neurons, which are required for memory consolidation in Drosophila, are sleep-promoting inhibitory neurons.

Evidence 1Source 1DOI PubMedprovenance

Supporting Sources

Source 1primary paper2015eLifeDOI PubMed

1 evidence snippet 4 linked claims Claim 1 Claim 2 Claim 3

Linked Claims

Claim 1assay resultsupports2015Source 1DOI PubMed

Functional imaging showed that DPM activation evokes robust chloride increases in mushroom body neurons but no detectable calcium or cAMP increases.

Claim 2conceptual linksupports2015Source 1DOI PubMed

Sleep regulation by neurons necessary for memory consolidation suggests sleep and memory consolidation are functionally interrelated through shared anatomy.

Claim 3functional rolesupports2015Source 1DOI PubMed

DPM neurons are sleep-promoting inhibitory neurons in Drosophila.

Claim 4mechanismsupports2015Source 1DOI PubMed

DPM neurons increase sleep by releasing GABA onto wake-promoting mushroom body α'/β' neurons.