First-pass extracted concept

Early growth response 1

Candidate: concept label1 source documents3 linked claims

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Aliases

EGR1

Evidence Snippets

The immediate early gene and transcription factor early growth response 1 (EGR1) has thus been revealed as a major mediator and regulator of synaptic plasticity and neuronal activity in both physiological and pathological conditions.

Evidence 1Source 1DOI PubMedprovenance

Supporting Sources

Source 1review2017Frontiers in Behavioral NeuroscienceDOI PubMed

1 evidence snippet 3 linked claims Claim 1 Claim 2 Claim 3

Linked Claims

Claim 1disease relevance summarysupports2017Source 1DOI PubMed

EGR1 is discussed in relation to pathological states, especially cognitive functions and neuropsychiatric disorders.

Quoted textsource-backed

Finally, we will discuss and illustrate the role of EGR1 in pathological states with a particular interest in cognitive functions and neuropsychiatric disorders.

Claim 2functional role summarysupports2017Source 1DOI PubMed

EGR1 is a major mediator and regulator of synaptic plasticity and neuronal activity in physiological and pathological conditions.

Quoted textsource-backed

The immediate early gene and transcription factor early growth response 1 (EGR1) has thus been revealed as a major mediator and regulator of synaptic plasticity and neuronal activity in both physiological and pathological conditions.

Claim 3review scope summarysupports2017Source 1DOI PubMed

Recent data, including genome-wide studies, describe a wide variety of genes, pathways, and biological functions regulated directly or indirectly by EGR1.

Quoted textsource-backed

we will analyze the amount of data, including genome-wide, that has emerged in the recent years describing the wide variety of genes, pathways and biological functions regulated directly or indirectly by EGR1