First-pass extracted concept

Egr1

Candidate: concept label1 source documents3 linked claims

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Evidence Snippets

Immediate Early Genes (IEGs) such as, c-fos, Egr1 and arc are selectively and promptly upregulated in learning and memory among neuronal subpopulations in regions associated with these processes.

Evidence 1Source 1DOI PubMedprovenance

Supporting Sources

Source 1review2018Frontiers in Behavioral NeuroscienceDOI PubMed

1 evidence snippet 3 linked claims Claim 1 Claim 2 Claim 3

Linked Claims

Claim 1evidence gapsupports2018Source 1DOI PubMed

Although many studies support changes in immediate early gene expression during learning and memory, few studies directly analyze the implication of these genes in mental illnesses.

Claim 2expression associationsupports2018Source 1DOI PubMed

Immediate early genes including c-Fos, Egr1, and Arc are selectively and rapidly upregulated during learning and memory in neuronal subpopulations associated with these processes.

Claim 3memory process associationsupports2018Source 1DOI PubMed

Changes in expression of c-Fos, Egr1, and Arc have been observed in recognition, working, and fear-related memories across the brain.