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engineering signalling pathways in mammalian cells

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Evidence Snippets

Here we describe cutting-edge genetic-engineering technologies for the rewiring of signalling networks in mammalian cells.

Evidence 1Source 1DOI PubMedprovenance

Supporting Sources

Source 1primary paper2024MEDDOI PubMed

1 evidence snippet 3 linked claims Claim 1 Claim 2 Claim 3

Linked Claims

Claim 1application statementsupports2024Source 1DOI PubMed

Designed signalling pathways can confer new properties on mammalian cells, including photosynthesis, detection of cancer and senescent cell markers, and synthesis of hormones or metabolites in response to chemical or physical stimuli.

Claim 2impact statementsupports2024Source 1DOI PubMed

Technologies for engineering signalling pathways in mammalian cells are advancing basic cellular biology, biomedical research, and drug discovery.

Claim 3scope statementsupports2024Source 1DOI PubMed

The paper describes genetic-engineering technologies for rewiring signalling networks in mammalian cells.