First-pass extracted concept

enteric cholinergic neuron optogenetic activation

Candidate: concept label1 source documents3 linked claims

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Aliases

optogenetic activation of enteric cholinergic neurons

Evidence Snippets

We demonstrate that optogenetic activation of enteric cholinergic neurons rapidly modulates intestinal physiology.

Evidence 1Source 1DOI PubMedprovenance

Supporting Sources

Source 1primary paper2025MEDDOI PubMed

1 evidence snippet 3 linked claims Claim 1 Claim 2 Claim 3

Linked Claims

Claim 1functional effectsupports2025Source 1DOI PubMed

Optogenetic activation of enteric cholinergic neurons rapidly modulates intestinal physiology.

Claim 2lineage specific functionsupports2025Source 1DOI PubMed

Different enteric neuronal lineages exert distinct regulatory roles, with cholinergic activation enhancing type-2 immunity-associated gene sets and tachykininergic neurons modulating distinct mucosal defense programs.

Claim 3microbe neuron interactionsupports2025Source 1DOI PubMed

Luminal introduction of Thomasclavelia ramosa remodels cholinergic-induced neuro-immunological transcription.