First-pass extracted concept

enteric neuroimmunophysiology

Candidate: concept label1 source documents3 linked claims

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Evidence Snippets

Here we underscore the importance of a holistic approach to gut physiology, placing an emphasis on intercellular connectedness, using enteric neuroimmunophysiology as the paradigm.

Evidence 1Source 1DOI PubMedprovenance

Supporting Sources

Source 1primary paper2024MEDDOI PubMed

1 evidence snippet 3 linked claims Claim 1 Claim 2 Claim 3

Linked Claims

Claim 1conceptual frameworksupports2024Source 1DOI PubMed

Gut physiology is shaped by interconnected neural, immune, hormonal, and external signals including the microbiome, diet, and physical environment.

Claim 2disease associationsupports2024Source 1DOI PubMed

Failure of gut communication and homeostatic systems can lead to acute or chronic disease including irritable bowel syndrome and inflammatory bowel disease.

Claim 3physiological rolesupports2024Source 1DOI PubMed

The gut integrates interactions between diverse cells and signaling molecules to support nutrient uptake and host defense.