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functional imaging

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Evidence Snippets

Here, we review the wealth of reagents available to map and manipulate neuronal activity with light.

Functional imaging demonstrates that DPM activation evokes robust increases in chloride in MB neurons, but is unable to cause detectable increases in calcium or cAMP.

Evidence 2Source 2DOI PubMedprovenance

Supporting Sources

Source 1review2018GeneticsDOI PubMed

1 evidence snippet 2 linked claims Claim 1 Claim 2

Source 2primary paper2015eLifeDOI PubMed

1 evidence snippet 1 linked claim Claim 1

Linked Claims

Claim 1model system positioningsupports2018Source 1DOI PubMed

Drosophila is presented as a premier model organism for studying how neural circuit activity patterns coordinate behavior because of its genetic tools and tractable brain complexity.

Claim 2review scopesupports2018Source 1DOI PubMed

The review covers reagents for using light to map and manipulate neuronal activity in Drosophila.

Claim 3assay resultsupports2015Source 2DOI PubMed

Functional imaging showed that DPM activation evokes robust chloride increases in mushroom body neurons but no detectable calcium or cAMP increases.