First-pass extracted concept

genetic code expansion

Candidate: concept label2 source documents3 linked claims

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Aliases

GCE

Evidence Snippets

Here we use genetic code expansion and bioorthogonal labelling to generate a panel of fluorescence-based biosensors

Evidence 1Source 1DOI PubMedprovenance

Genetic code expansion (GCE) technology has provided new tools to transform light insensitive proteins into novel photoreceptor proteins.

Evidence 2Source 2PubMedprovenance

Supporting Sources

Source 1primary paper2026MEDDOI PubMed

1 evidence snippet 0 linked claims

Source 2primary paper2017PubMedPubMed

1 evidence snippet 3 linked claims Claim 1 Claim 2 Claim 3

Linked Claims

Claim 1application scopesupports2017Source 2PubMed

Cas9 has been engineered to enable light activation of genomic editing by CRISPR.

Quoted textsource-backed

Very recently, Cas9 protein has been engineered to enable light activation of genomic editing by CRISPR.

Claim 2application scopesupports2017Source 2PubMed

Proteins including ion channels, GPCRs, transporters, and kinases have been rendered light responsive using genetic code expansion-enabled unnatural amino acid functionalities.

Quoted textsource-backed

Over the last two decades, various proteins including ion channels, GPCRs, transporters, and kinases have been successfully rendered light responsive owing to the functionalities of Uaas.

Claim 3method capabilitysupports2017Source 2PubMed

Genetic code expansion can transform light-insensitive proteins into novel photoreceptor proteins by site-specific incorporation of unnatural amino acids with light-sensitive moieties.

Quoted textsource-backed

Genetic code expansion (GCE) technology has provided new tools to transform light insensitive proteins into novel photoreceptor proteins. It is achieved by the site-specific incorporation of unnatural amino acids (Uaas) that carry light sensitive moieties