This review topic covers genetic approaches used to study morphology, connectivity, activity, and causal manipulation of neural circuits in non-human primates.
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genetic tools for neural circuit dissection in non-human primates
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Genetic tools have been widely applied in rodents to study specific-neuron morphology, pathway-selective connectome mapping, neuronal activity monitoring, and spatiotemporally resolved manipulation for understanding complex neural circuit formation, interactions, and functions.
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Genetic tools, which can be used for the morphology study of specific neurons, pathway-selective connectome mapping, neuronal activity monitoring, and manipulation with a spatiotemporal resolution, have been widely applied to the understanding of complex neural circuit formation, interactions, and functions in rodents.
The paper reviews progress in the development and application of genetic tools for brain studies in non-human primates and discusses advantages, limitations, and future perspective.
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In this review, we introduce the progress made in the development and application of genetic tools for brain studies on NHPs. We also discuss the advantages and limitations of each approach and provide a perspective for using genetic tools to study the neural circuits of NHPs.
Similar genetic approaches have been tried in non-human primates for neural-circuit dissection in neuroscience studies, but the field is still very preliminary.
Quoted textsource-backed
Recently, similar genetic approaches have been tried in non-human primates (NHPs) in neuroscience studies for dissecting the neural circuits involved in sophisticated behaviors and clinical brain disorders, although they are still very preliminary.