The purpose of this review is to compare existing PAI reporters and signal detection strategies, thereby offering a practical guide, particularly for the nonbiologist, to choosing the most appropriate reporter for maximum sensitivity in the biological and technological system of interest.
First-pass extracted concept
genetically encoded photoacoustic imaging reporters
Candidate: concept label1 source documents4 linked claims
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Evidence Snippets
Supporting Sources
Linked Claims
Reporter genes expressing absorbing proteins create the possibility of visualizing dynamic cellular and molecular processes with photoacoustic imaging.
Genetically encoded contrast in photoacoustic imaging is complementary to intrinsic contrast from endogenous absorbing chromophores such as hemoglobin.
Generating and detecting different types of genetically encoded photoacoustic reporters involves challenges and limitations.
Choosing the most appropriate photoacoustic imaging reporter depends on maximizing sensitivity within the biological and technological system of interest.