First-pass extracted concept

genomically stable gastric adenocarcinoma subtype

Candidate: concept label1 source documents3 linked claims

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Aliases

genomically stable tumours, GS

Evidence Snippets

We propose a molecular classification dividing gastric cancer into four subtypes: ... genomically stable tumours...

Evidence 1Source 1DOI PubMedprovenance

Supporting Sources

Source 1primary paper2014NatureDOI PubMed

1 evidence snippet 3 linked claims Claim 1 Claim 2 Claim 3

Linked Claims

Claim 1clinical implicationsupports2014Source 1DOI PubMed

Identification of the four molecular subtypes provides a roadmap for patient stratification and trials of targeted therapies.

Claim 2molecular classificationsupports2014Source 1DOI PubMed

The study proposes a molecular classification of gastric cancer into four subtypes: Epstein-Barr virus-positive, microsatellite unstable, genomically stable, and chromosomal instability.

Claim 3subtype associationsupports2014Source 1DOI PubMed

Genomically stable gastric tumours are enriched for the diffuse histological variant and mutations of RHOA or fusions involving RHO-family GTPase-activating proteins.