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First-pass extracted concept

GIBBERELLIN INSENSITIVE DWARF 1

Candidate: concept label1 source documents4 linked claims
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Aliases

GID1

Extracted Explainers

What the tool is doing

GID1 is described as the GA receptor. GA binding in a pocket of GID1 changes its conformation and increases its affinity for DELLA proteins.

Source 1DOIPubMed

What problem it solves

It provides the receptor-level mechanism that connects hormone binding to downstream DELLA degradation.

Source 1DOIPubMed

What it does not solve

The abstract does not specify receptor subtype differences, quantitative binding properties, or practical implementation details.

Source 1DOIPubMed

Alternatives

No alternative GA receptor is described in the abstract; GID1 is presented as the receptor in the core pathway model.

Source 1DOIPubMed

Evidence Snippets

DELLAs also promote transcription of the GA receptor, GIBBERELLIN INSENSITIVE DWARF 1 (GID1) ... A structural analysis of GID1 provides a model for understanding GA signaling.
Evidence 1Source 1DOIPubMedprovenance

Supporting Sources

Linked Claims

Claim 1evolutionary summarysupports2008Source 1DOIPubMed

Sequence analysis from Physcomitrella suggests that GID1 and DELLA components evolved early but did not initially interact.

Claim 2mechanistic summarysupports2008Source 1DOIPubMed

DELLA proteins promote transcription of the GA receptor GID1 and indirectly regulate GA biosynthesis genes, contributing to GA responsiveness and feedback control.

Claim 3mechanistic summarysupports2008Source 1DOIPubMed

GA binds within a pocket of GID1, changes GID1 conformation, and increases the affinity of GID1 for DELLA proteins.

Claim 4mechanistic summarysupports2008Source 1DOIPubMed

The GA-GID1-DELLA complex has increased affinity for an F-box protein, after which DELLAs are degraded via the proteasome and GA induces growth through DELLA degradation.