The review treats Hebbian plasticity as a core class of activity-dependent mechanisms that help refine neural circuit function.
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Hebbian plasticity
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Understanding of how Hebbian and homeostatic plasticity complement each other and sometimes interfere remains rudimentary.
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Nonetheless, our understanding of how these fundamentally distinct forms of plasticity compliment (and under some circumstances interfere with) each other remains rudimentary.
Key unresolved questions include the spatial and temporal scales of homeostatic and Hebbian mechanisms, which aspects of network function are under homeostatic control, and when segregation is required to prevent interference.
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These include unravelling the spatial and temporal scales of different homeostatic and Hebbian mechanisms, determining which aspects of network function are under homeostatic control, and understanding when and how homeostatic and Hebbian mechanisms must be segregated within neural circuits to prevent interference.
Hebbian and homeostatic plasticity mechanisms are widely understood to work together to refine neural circuit function.
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It has become widely accepted that homeostatic and Hebbian plasticity mechanisms work hand in glove to refine neural circuit function.