First-pass extracted concept

hepatoid adenocarcinoma of the uterine cervix

Candidate: concept label1 source documents7 linked claims
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Aliases

HAC of the cervix, HAC of the uterine cervix

Evidence Snippets

HAC of the uterine cervix is very rare and occurs mainly in postmenopausal women, and the first symptom is irregular vaginal bleeding in all cases, with elevated serum AFP values.
Evidence 1Source 1DOIPubMedprovenance

Supporting Sources

Linked Claims

Claim 1clinical featuresupports2025Source 1DOIPubMed

Reported hepatoid adenocarcinoma of the uterine cervix occurs mainly in postmenopausal women and presents with irregular vaginal bleeding and elevated serum AFP.

Quoted textsource-backed
HAC of the uterine cervix is very rare and occurs mainly in postmenopausal women, and the first symptom is irregular vaginal bleeding in all cases, with elevated serum AFP values.
Claim 2comparative pathologysupports2025Source 1DOIPubMed

Hepatoid adenocarcinoma of the cervix is more prone to metastasis and has worse prognosis than ordinary cervical adenocarcinoma.

Quoted textsource-backed
HAC of the cervix is more prone to metastasis than ordinary cervical adenocarcinoma, and its prognosis is worse.
Claim 3disease associationsupports2025Source 1DOIPubMed

Hepatoid adenocarcinoma is often associated with elevated serum alpha-fetoprotein.

Quoted textsource-backed
Hepatoid adenocarcinoma (HAC) is a specific extrahepatic adenocarcinoma with hepatocellular differentiation, often associated with elevated serum alpha-fetoprotein (AFP).
Claim 4literature countsupports2025Source 1DOIPubMed

Only two cases of hepatoid adenocarcinoma of the uterine cervix had been reported in the literature at the time of publication.

Quoted textsource-backed
Only two cases have been reported in the literature
Claim 5pathogenesis statementsupports2025Source 1DOIPubMed

The pathogenesis of hepatoid adenocarcinoma is mainly related to hepatoid differentiation, gene mutation, and inflammatory stimulation.

Quoted textsource-backed
With the development of molecular pathology and next-generation sequencing technology, the pathogenesis of HAC is mainly related to hepatoid differentiation, gene mutation, and inflammatory stimulation.
Claim 6raritysupports2025Source 1DOIPubMed

Hepatoid adenocarcinoma of the uterine cervix is very rare.

Quoted textsource-backed
HAC of the uterine cervix is very rare
Claim 7treatment practicesupports2025Source 1DOIPubMed

Treatment of hepatoid adenocarcinoma of the cervix follows cervical cancer surgical management with postoperative radiotherapy or platinum-based combination chemotherapy.

Quoted textsource-backed
The treatment plan still refers to the surgical treatment plan for cervical cancer, and radiotherapy or platinum-based combination chemotherapy is given after surgery.