Hypothalamic and brainstem neuronal circuits are critically involved in the sensing of circulating and local factors conveying information about the energy status of the organism.
First-pass extracted concept
homeostatic energy balance
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Recent advances in mouse genetics, electrophysiology, and optogenetic techniques have greatly contributed to improving understanding of homeostatic energy-balance regulation.
Hypothalamic and brainstem neuronal circuits are critically involved in sensing circulating and local factors that convey organismal energy status.
Integration of energy-status signals by these circuits generates coordinated physiological responses that regulate appetite and energy expenditure.